Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Inhibitory effect of Lonicera Japonica on trypsin-induced inflammatory mediator secretion from human leukemic mast cells

  • Kang, Ok-Hwa (Department of Oriental Pharmacy,College of Pharmacy, Wonkwang University) ;
  • Kim, Jin-Ah (Department of Oriental Pharmacy,College of Pharmacy, Wonkwang University) ;
  • Baek, Ok-Seon (Department of Oriental Pharmacy,College of Pharmacy, Wonkwang University) ;
  • Lee, Young-Mi (Department of Oriental Pharmacy,College of Pharmacy, Wonkwang University)
  • Published : 2002.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Mast cells play an important role in inflammation by functioning as a source of histamine, tryptase, and proinflammatory cytokines. Lonicera Japonica (Caprifoliaceae. Lc) has been used to treat inflammation. We investigated whether the water extract of Lonicera Japonica(Lc) inhibit production of inflammatory mediators such as tryptase and tumor-necrosis factor (TNF)-${\alpha}$, and phosphorylation of extracellular signal-regulated kinase(ERK) in trypsin-stimulated HMC-1. (omitted)

Keywords