Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.245.1-245.1
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- 2002
Inhibitory effects of resveratrol analogs on lipopolysaccharide-induced cyclooxygenase-2 activity in RAW264.7 cells
- Park, Eun-Jung (College of Pharmacy, Ewha Womans University) ;
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Min, Hye-Young
(College of Pharmacy, Ewha Womans University)
;
- Park, Jae-Eun (Natural Product Research Institute) ;
- Kim, Sang-Hee (Natural Product Research Institute) ;
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Lee, Sang-Kook
(College of Pharmacy, Ewha Womans University)
- Published : 2002.10.01
Abstract
It has been known that resveratrol, a phytoalexin present in grapes mainly, has antioxidant. anti-inflammatory, and cancer chemopreventive activity. One mechanism of its anti-inflammation and cancer prevention is considered to modulate cyclooxygense-2 (COX-2) activity. Since COX-2 plays an important role in inflammation and carcinogenesis, the potential COX-2 inhibitors have been considered as anti-inflammatory or cancer chemopreventive agents. (omitted)
Keywords