대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
- /
- Pages.223-224
- /
- 2002
Pharmacokinetic and Pharmacodynamic Modeling of a Proton Pump Inhibitor
-
Bae, Kyun-Seop
(Asan Medical Center and College of Medicine, Seoul National University)
;
- Jang, In-Jin (Asan Medical Center and College of Medicine, Seoul National University)
- 발행 : 2002.10.01
초록
Pharmacokinetic (PK) and pharmacodynamic (PD) study of a new reversible proton pump inhibitor (YH1885, Yuhan Pharmaceutical Co.) was done as a phase 1 clinical trial in Seoul national University Hospital Clinical trialcenter. Single dose of 60, 100, 150, 200, and 300mg were administered to total 20 healthy subjects under fasting state. Six subjects were given 100 mg after food and 12 subjects were given multiple doses of 150 and 300 mg every day for 7 days under fasting state. (omitted)
키워드