Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.88-89
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- 2002
High Throughput Screening System for Kinetics of Brain Influx
Abstract
Traditionally, kinetics of brain influx of drugs has been evaluated by a number of experimental techniques. Brain uptake index and in situ brain perfusion study have been used for the determination of the kinetics; However, these methods generally focus on the accuracy of the uptake rate into the brain rather than the speed of the determination. In addition, application of radiolabelled substrates (e.g.,
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