Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Purinoceptor and Intracellular $Ca^{2+}$ Regulation in Rat Prostate N euronencocrine Cells

  • Kim, Jun-Hee (Department of Physiology, Sungkyunkwan University School of Medicine) ;
  • Nam, Joo-Hyun (Department of Physiology, Sungkyunkwan University School of Medicin) ;
  • Uhm, Dae-Yong (Department of Physiology, Sungkyunkwan University School of Medicin) ;
  • Kim, Sung-Joon (Department of Physiology, Sungkyunkwan University School of Medicine)
  • Published : 2002.06.01
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Abstract

Extracellular ATP regulates a wide range of cellular function including the growth of prostate gland. Purinoceptors (ATP receptors) are divided into P2X (ligand-gated ion channels) and P2Y (G-protein-coupled receptor) subfamilies. In the present study, we investigated the types of purinoceptors in rat prostate neuroendocrine (RPNE) cells using whole-cell patch clamp technique, intracellular $Ca^{2+}$ measurement and RT-PCR analysis.(omitted)d)

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