Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Altered Sarcoplasmic Reticulum $Ca^{2+}$ Uptake of H9c2 Cells Cultured in High Glucose Medium

  • Lee, Eun-Hee (Department of Pharmacology, University of Ulsan College of Medicine) ;
  • Seo, Young-Joo (Department of Pharmacology, University of Ulsan College of Medicin) ;
  • Lee, Jun-Whee (Department of Pharmacology, University of Ulsan College of Medicin) ;
  • Jang, Joong-Sik (Department of Pharmacology, University of Ulsan College of Medicin) ;
  • Kim, Young-Hoon (Department of Pharmacology, University of Ulsan College of Medicin) ;
  • Kim, Hae-Won (Department of Pharmacology, University of Ulsan College of Medicine)
  • Published : 2002.06.01
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Abstract

Altered intracellular $Ca^{2＋}$ homeostasis is presumably the primary mechanism of the diastolic impairment in diabetic cardiomyopathy. However, causal relations of numerous environmental changes observed in the diabetic heart have been left unresolved. In the present study, we sought to establish an in vitro model of diabetic cardiomyopathy using H9c2 cardiac myocyte cell line.(omitted)

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