Measuring of $Na^+-Ca^{2+}$ Exchange Current in Cerebellar Purkinje Cells

  • Cho, Chung-Hyun (Department of Life Science, Division of Molecular and Life Science, Pohang University of Science and Technology) ;
  • Daejong Jeon (National CRI Center for Calcium and Learning, Korea Institute of Science and Technolog) ;
  • Shin, Hee-Sup (National CRI Center for Calcium and Learning, Korea Institute of Science and Technolog) ;
  • Lee, Chin O. (Department of Life Science, Division of Molecular and Life Science, Pohang University of Science and Technology)
  • 발행 : 2002.06.01

초록

The Na$^{+}$-Ca$^{2+}$ exchanger (NCX) is known to playa critical role in the regulation of intracellular $Ca^{2+}$ in many tissues and cells. Three isoforms have been cloned (NCXl, NCX2, NCX3). Among the isoforms, NCX2 and NCX3 are expressed at high levels in brain and in a few other tissues. But the differential properties of the isoforms are not yet clearly established.(omitted)

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