Mitochondrial DNA Heteroplasmy in Cloned Bovine Embryos following Somatic Cell Nuclear Transfer

  • Do, Jeong-Tae (Animal Resources Research Center, Konkuk University, Infertility Research Laboratory, Department of OB & GYN, Kyung Hee University Medical Center) ;
  • Lee, Bo-Yon (Infertility Research Laboratory, Department of OB & GYN, Kyung Hee University Medical Cente) ;
  • Kim, Seung-Bo (Infertility Research Laboratory, Department of OB & GYN, Kyung Hee University Medical Cente) ;
  • Lee, Hoon-Taek (Animal Resources Research Center, Konkuk University) ;
  • Chung, Kil-Saeng (Animal Resources Research Center, Konkuk University)
  • Published : 2002.06.01

Abstract

Nuclear transfer (NT) has the potential to produce large number of identical progeny and would greatly benefit ongoing research efforts, Cloned animals produced by NT, however, may not be genetically identical to the donor cell. In NT procedures, nucleus genes originate from donor cell, and mitochondrial genes originate from recipient oocytes. (omitted)

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