Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2002.06a
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- Pages.10-10
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- 2002
Comparisons of Gene Expression Profiles between IVF and Cloned Embryo
- Han, Dong-Wook (Animal Resource Research Center, Konkuk University) ;
- Kim, Eun-Ha (Animal Resource Research Center, Konkuk University) ;
- Kim, Kee-Pyo (Animal Resource Research Center, Konkuk University) ;
- Chung, Kil-Saeng (Animal Resource Research Center, Konkuk University) ;
- Lee, Hoon-Taek (Animal Resource Research Center, Konkuk University)
- Published : 2002.06.01
Abstract
The low efficiency of animal production by nuclear transfer technique is considered to be result of an incomplete reprogramming of the donor cell nucleus, which leads to a lack of, or abnormal expression of developmentally important genes. There are a lot of genes related to embryo development and some of these genes are regulated by imprinting. IGF2 (insulin like growth factor 2) and IGF2R (IGF2 receptor) that play important roles in preimplantation development are included in imprinted genes also. (omitted)