Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.123-123
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- 2002
EFFECT OF PHYSOSTIGMINE PRETREATMENT ON PARATHION TOXICITY IN RATS
- Kim, Sung-Y (College of Pharmacy, Seoul National University) ;
- Park, Kwon-H (College of Pharmacy, Seoul National University) ;
- Lee, Myung-G (College of Pharmacy, Seoul National University) ;
- Kim, Young-C (College of Pharmacy, Seoul National University)
- Published : 2002.05.01
Abstract
Abstract The protective effects of physostigmine against the toxicity of parathion (diethyl-4-nitrophenyl phosphorothionate) were examined in male Sprague-Dawley rats. Physostigmine (100 or 1,000 ㎎/㎏, ip) injected 30 min before decreased the inhibition of acetylcholinesterase (AChE) activities in brain, lung and blood induced by parathion (2 ㎎/㎏, ip).(omitted)