SUPPRESSION OF EXPERIMENTAL LIVER TUMORS BY ESTROGEN TREATMENT OR CASTRATION IN MALE RATS

  • Kang, Jin-Seok (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Che, Jeong-Hwan (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Ahn, Byeongwoo (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Lee, Kookkyung (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Nam, Ki-Taek (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Choi, Mina (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Seyl (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Jung, Jin-Jung (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Jang, Dong-Deuk (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Yang, Ki-Hwa (National Institute of Toxicological Research, Korea Food and Drug Administration)
  • Published : 2002.05.01

Abstract

It has been reported that the incidence of liver cancer in human is markedly sex-differentiated, with a much higher frequency in men than in women. In experimental animals, male have higher incidence of liver tumor than female in carcinogen-induced tumors as well as spontaneous tumors.(omitted)

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