Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.90-90
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- 2002
COX-INHIBITORS DOWN-REGULATE Cyplal ACTIVITY IN C57BL/6 MOUSE AND Hepa I CELLS.
- Syrie Bang (College of Pharmacy, Ewha Womens University) ;
- Kim, Ja-Young (College of Pharmacy, Ewha Womens University) ;
- Sheen, Yhun-Yhong (College of Pharmacy, Ewha Womens University)
- Published : 2002.05.01
Abstract
In order to understand the mechanism of action of TCDD, we have examine the effect of COX-inhibitors on Cyp1a1 activity. We observed the effect of COX-inhibitor on EROD activity in C57BL/6 mouse in vovo. And we also evaluated the effect of COX-inhibitors on mouse cyp1a1 promoter activity in Hepa cell.(omitted)