Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.81-81
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- 2002
ALTERED GENE EXPRESSION IN RADIATION INDUCED TUMORIGENESIS OF NIH3T3 CELLS REVEALED BY MICROARRAY
- Kang, Chang-Mo (Korea Cancer Center Hospital) ;
- Song, Ji-Eun (Korea Cancer Center Hospital) ;
- Cho, Chul-Koo (Korea Cancer Center Hospital) ;
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Lee, Su-Jae
(Korea Cancer Center Hospital)
;
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Lee, Yun-Sil
(Korea Cancer Center Hospital)
- Published : 2002.05.01
Abstract
The recent development of cDNA microarray or cDNA chip technology has made it possible to analyze the expression of thousands of genes at once. In present study, we made radioresistant clones (#1 and #4) from NIH3T3 cells which are not tumorigenic and we identified 4 genes using microarray system, cdk6, cdc25B, mdm-2 and nidogene, which were altered in radiaiton resistanct NIH3T3 cells.(omitted)