Inhalation toxicity study of H menthol (Nicotine free-tob acco free)herbal cigarettes

  • Jung, Ji-Won (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Cho, Sung-Dae (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Cho, Jong-Ho (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Kyung-Bae (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Ji-Hae (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Ahn, Nam-Shik (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Yang, Se-Ran (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Park, Joon-Suk (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Yong-Soon (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Kang, Kyung-Sun (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University)
  • Published : 2002.05.01

Abstract

Generally, tobacco smoking has noxious effects such as DNA damage, lung cancer induction, coronary artery disease. Nowadays, as concerns on health and longevity increases, a huge variety of products that aim to assist to quit smoking or reduce addictive symptoms such as nicotine patches are developed and manufactured with safely evaluation, but the safety of the most recent products of interest which do not contain tobacco and nicotine, and shape cigarettes is not evaluated and guaranteed relatively. In this study, we used H-menthol(nicotine free-tobacco fine) which are widely consumed through the world to evaluate the single and repeated dose inhalation toxicity and genotoxicity of H menthol (Nicotine free-tobacco free) herbal cigarettes provided by Cigastop Ltd. in ICR mice.

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