Proceedings of the Korea Society of Environmental Toocicology Conference (한국환경독성학회:학술대회논문집)
- 2001.05a
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- Pages.129-129
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- 2001
Mutation Spectrum of 1, 2-Dibromo-3-chloropropane, an Endocrine Disruptor, in the lacI Transgenic Big $\textrm{Blue}^{(R)}$ Rat2 Fibroblast Cell Line.
- Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science ＆ Technology) ;
- Chai, Young-Gyu (Department of Biochemistry and molecular Biology, Hanyang University) ;
- Lee, Kilchul (National Institute of Environmental Researc) ;
- Kyounghee Oh (National Institute of Environmental Researc) ;
- Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science ＆ Technology)
- Published : 2001.05.01
Abstract
1,2-Dibromo-3-chloropropane (DBCP), a soil fumigant against nematodes, is a genotoxic carcinogen and also is classified by World Wildlife Fund as endocrine disruptors. DBCP has been extensively studied on genotoxicity, carcinogenicity, and damage in male reproductive-related organs. However, information on precise mechanism of mutagenesis and carcinogenesis of DBCP is yet unknown. (omitted)
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