Proceedings of the Korea Society of Environmental Toocicology Conference (한국환경독성학회:학술대회논문집)
- 2001.05a
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- Pages.125-125
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- 2001
Estrogenic Activity Assessment of Alkylphenolic chemicals using in vitro assays : I. E-Screen Assay
- Park, Hyo-Joung (Toxicology Laboratory, Korea Institute of Science and Technology) ;
- Lee, Ho-Sa (Department of Biology, Kyunghee University) ;
- Na, Jin-Gyun (National Institute of Environmental Researc) ;
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Ryu, Jae-Chun
(Toxicology Laboratory, Korea Institute of Science and Technology)
- Published : 2001.05.01
Abstract
It has been hypothesized that environmental estrogens may play roles in the increasing incidence of breast and testicular cancers and another problems of the reproductive systems. Alkylphenols which are widely used as plastic additives and surfactants have been shown to induce estrogenic responses. The E-screen assay was developed to assess the estrogenedity of environmental chemicals using the profiferation effect of estrogens on their target cells as an end point. (omitted)
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