Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
권호 표지

Regulation of p53 Expression in an Acidic Environment after Radiation

  • Park, E-K (Department of Therapeutic Radiology, College of Medicine, Ulsan University) ;
  • Chung, H-S (Department of Microbiology, College of Medicine, Inha University) ;
  • Rhee, Y-H (Department of Therapeutic Radiology, College of Medicine, Ulsan University) ;
  • Ha, S-W (Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
  • Song, C-W (Department of Therapeutic Radiology, College of Medicine, University of Minnesot) ;
  • Park, H-J (Department of Microbiology, College of Medicine, Inha University)
  • Published : 2001.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to investigate the molecular mechanism by which environmental pH alters the radiation-induced expression of p53, the key regulator of cellular responses to radiation. We have already reported that an acidic environment markedly prolongs the radiation-induced expression of p53 and also prolongs the radiation-induced G2/M arrest.(omitted)

Keywords