ANALYSIS OF CHROMOSOME ABERRATION, SISTER CHROMATID EXCHANGE, MICRONUCLEI AND SINGLE CELL GEL ELECTROPHORESIS IN HUMAN LYMPHOCYTES EXPOSED IN VITRO TO BISPHENOL A AND DIETHYLSTILBESTROL

  • Published : 2001.10.01

Abstract

Endocrine disruptors have been implicated in carcinogenesis in animal studies, but carcinogenetic effects on human remain controversial. In order to examine the genotoxicity of two common endocrine disruptors, Bisphenol A and Diethylstilbestrol, cytogenetic endpoints including chromosome aberration(CA), sister chromatid exchange (SCE), micronuclei (MN) analyses and DNA damage by single cell gel electrophoresis (SCGE) were assayed.(omitted)

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