Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.46-47
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- 2001
CHLOROPHYLLIN REDUCES URINARY LEVELS OF A CARCINOGEN-DNA ADDUCT BIOMARKER IN A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
- Egner, Patricia (Johns Hopkins University Bloomberg School of Public Health) ;
- Wang, Jin-Bing (Qidong Liver Cancer Institute) ;
- Zuh, Yuan-Rong (Qidong Liver Cancer Institute) ;
- Zhang, Bao-Chu (Qidong Liver Cancer Institute) ;
- Wu, Yan (Qidong Liver Cancer Institute) ;
- Zhang, Qi-Nan (Qidong Liver Cancer Institute) ;
- Qian, Geng-Sun (Shanghai Cancer Institute) ;
- Kuang, Shuang-Yuan (Shanghai Cancer Institute) ;
- Gange, Stephen (Johns Hopkins University Bloomberg School of Public Health) ;
- Jacobson, Lisa (Johns Hopkins University Bloomberg School of Public Health) ;
- Helzlsouer, Kathy (Johns Hopkins University Bloomberg School of Public Health) ;
- Bailey , George (Oregon State Univ.) ;
- Groopman, John (Johns Hopkins University Bloomberg School of Public Health) ;
- Kensler, Thomas (Johns Hopkins University Bloomberg School of Public Health)
- Published : 2001.10.01
Abstract
Residents of Qidong, Peoples Republic of China, are at high risk for development of hepatocellular carcinoma, in part due to consumption of foods contaminated with aflatoxins. Chlorophyllin, a mixture of semi-synthetic, water-soluble derivatives of chlorophyll that is used as a food colorant and over-the-counter medicine, has been shown to be an effective inhibitor of aflatoxin hepatocarcinogenesis in animal models.(omitted)
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