Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.28-28
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- 2001
EXPERIMENTAL STUDIES FOR PREVENTION OF LARGE BOWEL CARCINOGENESIS; A NEW BIOMARKER AND ITS ROLE
- Mori, Hideki (Department of Pathology, Gifu University School of Medicine) ;
- Yamada, Yasuhiro (Department of Pathology, Gifu University School of Medicin) ;
- Hirose, Yoshinobu (Department of Pathology, Gifu University School of Medicin) ;
- Hara, Akira (Department of Pathology, Gifu University School of Medicin) ;
- Kuno, Toshiya (Department of Pathology, Gifu University School of Medicine)
- Published : 2001.10.01
Abstract
Large bowel cancer is one of the major causes of increasing world-wide cancer mortality. Our group has found a variety of naturally-occurring and synthetic compounds which have chemopreventive potentials against the occurrence of large bowel cancers using animal models. Aberrant crypt foci (ACF) which develop in rodents soon after the carcinogen exposure have been used as a biomarker for screening effective agents for cancer chemoprevention.(omitted)
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