한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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- Pages.24-25
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- 2001
ETHENO-DNA ADDUCTS AS OXIDATIVE STRESS-MARKERS IN CANCER ETIOLOGY AND CHEMOPREVENTION STUDIES
- Bartsch, H. (Division of Toxicology and Cancer Risk Factors, German Cancer Research Center (DKFZ)) ;
- Nair, J. (Division of Toxicology and Cancer Risk Factors, German Cancer Research Center (DKFZ) ;
- Owen, R. (Division of Toxicology and Cancer Risk Factors, German Cancer Research Center (DKFZ))
- 발행 : 2001.10.01
초록
Persistent cellular oxidative stress and enhanced lipid peroxidation (LPO) of PUFAs, leading to macromolecular damage and disruption of signaling pathways, are implicated in the development of human malignancies and other chronic degenerative diseases. LPO generates by oxidation of linoleic acid (LA) or arachidonic acid (
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