CELL-DEATH MECHANISMS OF MPTP-INDUCED PARKINSONISM

  • Kim, J.M. (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • Park, C.W. (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • J.J. O (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • T.S. Kang (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • K.W. Seo (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • S.K. Seo (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • Kim, K.B. (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • Kim, J.W. (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA) ;
  • Lee, S.H. (Dept. of Pharmacol. National Institute of Toxicological Research, KFDA)
  • 발행 : 2001.05.01

초록

The cause of Parkinson's disease (PD) is largely unknown. However, free radical toxicity may playa role in the degeneration of substantia nigra, which is the major focus of pathological damages in PD. Recently, a neuroprotective effect of nicotine in PD has been suggested.(omitted)

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