한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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- Pages.117-117
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- 2001
COMBINED IN VITRO ASSAY FOR 3T3 NRU PT ASSAY AND PHOTOHEMOLYSIS AS PART OF PHOTOTOXICITY TEST
- Chunja Nam (Skin Research Institute, Pacific R＆D Center) ;
- Kim, Baehwan (Skin Research Institute, Pacific R＆D Center) ;
- Lee, Byoungseok (Skin Research Institute, Pacific R＆D Center) ;
- Seongjoon Moon (Skin Research Institute, Pacific R＆D Center) ;
- Ihseop Chang (Skin Research Institute, Pacific R＆D Center)
- 발행 : 2001.05.01
초록
The aim of this study was to assess a possible alternative method as replacement for in vivo phototoxicity test. The 3T3 mouse fibroblast neutral red uptake phototoxicity assay (3T3 NRU PT assay) is a screening method for studying DNA or cellular damage. Photohemolysis assay is a mechanistic study for investigating oxygen-dependent membrane damage.(omitted)
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