Assessment of autoimmunogenic potential of autoimmune disease inducing chmecals using the popliteal lymph node assay

  • Kim, Hyung-Soo (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Juno H. Eom (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Jin-Ho (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Chung, Seung-Tae (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Park, Jae-Hyun (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kang, Sun-Kyung (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Dong-Sub (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration)
  • Published : 2001.05.01

Abstract

The popliteal lymph node assay (PLNA) was proposed to predict autoimmunogenic potential of xenobiotics. This study was conducted to establish the popliteal lymph node assay(PLNA) and to investigate the measurement of lymphocyte subsets can be utilized as an additional parameter in PLNA.(omitted)

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