IL-6 and IL-10 in experimentally induced rat pulpal inflammation

  • Chang, Seok-Woo (Department of Conservative Dentistry, College of Dentistry, Seoul Nat. Univ.) ;
  • Lim, Sung-Sam (Department of Conservative Dentistry, College of Dentistry, Seoul Nat. Univ.)
  • Published : 2001.11.01

Abstract

IL-6 and IL-10 are known to be inflammatory cytokines that mediate host response to invading microorganisms or pathogenic antigen. But the roles of these cytokines in pulpal inflammation are not well established. The objective of this study was to investigate the concentrations and the roles of IL-6 and IL-10 in the pulpal inflammation associated with gram-negative bacteria, P. nigrescens. We exposed the pulps of rat mandibular incisors and inserted sterile cotton in control groups and inoculated P. nigrescens in experimental groups.(omitted)

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