The effect of the dissolved oxygen concentration on the production of manganese peroxidase by Phaenerochaete chrysosporium

The effect of the dissolved oxygen (DO) concentration on the production of manganese peroxidase by Phaenerochaete chrysosporium was studied in the immobilized reactor system. The oxygen levels significantly affected the production of manganese peroxidase (MnP) as well as that of $H_2O_2$. It is known that a high oxygen level is required to produce this enzyme. In this study, however, higher DO concentrations above a critical DO concentration inhibited MnP production. It is thought that a greater $H_2O_2$ production seen with higher DO concentrations caused adverse effects on the MnP production. On the other hand, with lower DO concentrations, $H_2O_2$ did not accumulate enough to stimulate MnP production.

본 연구는 용존산소의 양에 따른 MnP의 생산양상을 체계적으로 연구하였으며, 과량의 산소 공급 시 MnP 생산이 저해될 수 있음을 산소공급에 따른 과량의 $H_2O_2$생산 측면에서 설명하고 있다. 또한 보다 높은 MnP 생산을 위한 산소공급방법을 제시하고자 하였다.