대한생식의학회:학술대회논문집
- 2000.06a
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- Pages.29-35
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- 2000
The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility
- Sharma, Rakesh K. (Center for Advanced Research in Human Reproduction and Infertility, Departments of Urology, Gynecology-Obstetrics, Biostatistics and Epidemiology. The Cleveland Clinic Foundation) ;
- Pasqualotto, Fabio F. (Center for Advanced Research in Human Reproduction and Infertility, Departments of Urology, Gynecology-Obstetrics, Biostatistics and Epidemiology. The Cleveland Clinic Foundation) ;
- Nelson, David R. (Center for Advanced Research in Human Reproduction and Infertility, Departments of Urology, Gynecology-Obstetrics, Biostatistics and Epidemiology. The Cleveland Clinic Foundation) ;
- Thomas Jr, Anthony J. (Center for Advanced Research in Human Reproduction and Infertility, Departments of Urology, Gynecology-Obstetrics, Biostatistics and Epidemiology. The Cleveland Clinic Foundation) ;
- Agarwal, Ashok (Center for Advanced Research in Human Reproduction and Infertility, The Cleveland Clinic Foundation)
- Published : 2000.06.02
Abstract
The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in seminal fluid indicates oxidative stress and is correlated with male infertility. A composite ROS-TAC score may be more strongly correlated with infertility than ROS or TAC alone. We measured ROS, TAC, and ROS-TAC scores in semen from 127 patients and 24 healthy controls. Of the patients, 56 had varicocele, eight had varicocele with prostatitis, 35 had vasectomy reversals, and 28 had Idiopathic infertility. ROS levels were higher among infertile men, especially those with varicocele with prostatitis (mean