대한핵의학회:학술대회논문집

The Korean Society of Nuclear Medicine (대한핵의학회)
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Dosimetry and MIRD for Re-188 Liquid Balloons

Re-188-DTPA 풍선 주위 선량분포와 의용내부피폭선량

  • Lee, Dong-Soo (Departments of Nuclear Medicine, Seoul National University Hospital) ;
  • Lee, Jin (Departments of Physics, Ewha Womans University)
  • 이동수 (서울대학교 의과대학 핵의학교실) ;
  • 이진 (이화여자대학교 물리학과)
  • Published : 1999.05.21
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Abstract

Re-188 is suitable for endovascular liquid-balloon brachytherapy for the prevention of restenosis after angioplasty. Re-188 was concentrated to 3700 MBq/ml and labeled with DTPA. According to dosimetric calculation, it took 420 seconds using Re-188 solution with concentration of 3700 MBq/ml to irradiate 17.6 Gy to the target at 1 mm from the balloon surface. Software was made to estimate the irradiation time. MIRD calculation with dynamic bladder model yielded the whole body dose of Re-188-DTPA as 0.005 mGy/MBq in case of balloon rupture and release of the whole amount into the blood.

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