한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)
- 한국생물물리학회 1999년도 학술발표회 진행표 및 논문초록
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- Pages.64-64
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- 1999
Blockade of the HERG Human Cardiac $K^+$ Channel by the Antidepressant Drug Amitriptyline
- Jo, Su-Hyun (Department of Life Science, Pohang University of Science and Technology) ;
- Lee, Chin. O. (Department of Life Science, Pohang University of Science and Technolog) ;
- Yung E. Earm (Department of Physiology, Seoul National University College of Medicin) ;
- Ho, Won-Kyung (Department of Physiology, Seoul National University College of Medicine)
- 발행 : 1999.06.01
초록
Amitriptyline has been known to induce QT prolongation and ventricular arrhythmias such as torsades de pointes which causes sudden death. We studied the effects of amitriptyline on the human ether-a-go-go-related gene (HERG) channel expressed in Xenopus oocytes.(omitted)
키워드