한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)

한국생물물리학회 (The Korean Biophysical Society)
권호 표지

ATP Modulation of Cloned Rat Brain Large-conductance $Ca^{2+}$-activated $K^+$ Channel by Protein Phosphorylation

  • Park, S.Y. (Department of Physiology, College of Medicine, Chung-Ang Univ.) ;
  • S. Chung (Department of Physiology, College of Medicine, Chung-Ang Univ.)
  • 발행 : 1999.06.01
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초록

Large conductance $Ca^{2＋}$-activated $K^{＋}$ channels (Maxi-K channel) have been implicated in many important physiological processes such as co-ordination of membrane excitability in neurons. Modulation of these channels are archived by the activity of various protein kinases. The most widely studied example of Maxi-K channel regulation by protein phosphorylation has been obtained using plasma membranes from the rat brain incorporated into lipid bilayers.(omitted)

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