Effect of Angiotensin II on Synaptic Transmission in the Rat Subfonical Organ

  • Lee, Ho-Sung (Dept. of Pharmacol., Coll. of Vet. Med., Seoul Nat′l Univ.) ;
  • Han, Seong-Kyu (Dept. of Pharmacol., Coll. of Vet. Med., Seoul Nat′l Univ) ;
  • Ryu, Pan-Dong (Dept. of Pharmacol., Coll. of Vet. Med., Seoul Nat′l Univ.)
  • 발행 : 1999.06.01

초록

Circulating substances can directly access the neurons in circumventricular organ (CVO) located on the border of cerebral ventricles. The neurons in CVO are considered to playa pivotal role in blood-brain communication. In subfonical organ (SFO), a CVO in forebrain, angiotensin II (AII) is mown to reduce A type $K^{+}$ current and input resistance, but enhance firing rate.(omitted)

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