Spermine Modulation of Maxi-K Channels in Gastric Smooth Muscle Cells

  • Kang, Tong-Mook (Department of Physiology, Sungkyunkwan University, School of Medicine) ;
  • Kim, Chun-Hee (Department of Physiology, Sungkyunkwan University, School of Medicin) ;
  • Park, Myoung-Kyu (Department of Physiology, Sungkyunkwan University, School of Medicin) ;
  • Rhee, Poong-Lyul (Department of Medicine, Sungkyunkwan University, School of Medicin) ;
  • Uhm, Dae-Yong (Department of Physiology, Sungkyunkwan University, School of Medicine)
  • Published : 1999.06.01

Abstract

Polyamines are polyvalent cations which are ubiquitously present in pro- and eukaryotic cells. In the present study we investigated the action mechanism of spermine$\^$+4/ (C$\sub$10/), a natural polyamine, on the large-conductance Ca$\^$2+/-activated K (maxi-K) channel using excised patches from the human gastric smooth muscle.(omitted)

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