한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)
- 한국생물물리학회 1999년도 학술발표회 진행표 및 논문초록
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- Pages.41-41
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- 1999
Regulation of the Inhibitory Function of $\alpha_1$ -Antitrypsin by Native Metastability
- Lee, Cheolju (National Creative Research Initiative Center, Korea Research Institute of Bioscience and Biotechnology) ;
- Yu, Myeong-Hee (National Creative Research Initiative Center, Korea Research Institute of Bioscience and Biotechnology)
- 발행 : 1999.06.01
초록
The native forms of some proteins such as inhibitory serpins (serine protease inhibitors) and viral membrane fusion proteins are metastable, which is critical to their functions. To understand the mechanism of how native metastability regulates the inhibitory function of serpins, we characterized stabilizing mutations of
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