The Underlying Mechanisms of Cardiac Dysfunction in Diabetes Mellitus

  • Kim, Rae-Won (Department of Pharmacology, University of Ulsan College of Medicine)
  • 발행 : 1999.06.01

초록

Diabetic cardiomyopathy has been suggested to be caused by the intracellular Ca$\^$2+/ overload in the myocardium. We have investigated the possible mechanism of the functional defect of cardiac sarcoplasmic reticulum (SR) in diabetic rats with respect to Ca$\^$2+/-ATPase and phospholamban (PLB) at the transcriptional and translational levels.(omitted)

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