The Solution Structure of FADD Death Domain: Structural Basis of Death Domain Interactions of Fas and FADD

  • Jeong, Euj-Jun (Graduate School of Biotechnology, Korea University) ;
  • SookHee, Bang (Department of Biology, Korea University) ;
  • Kim, Key-Sun (Structural Biology Center, Korea Institute of Science and Technology, Korea University)
  • Published : 1999.06.01

Abstract

A signal of Fas-mediated apoptosis is transferred through an adaptor protein FADD by interactions between death domains of Fas and FADD. To understand the signal transduction mechanism of Fas-mediated apoptosis, we solved the solution structure of a murine FADD death domain.(omitted)

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