Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 1999.10a
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- Pages.46-57
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- 1999
The Production of Anti-cancer Substances by in vitro Grown Cultures of Panax ginseng C.A. Meyer
- Yang, Deok-Chun (Korea Ginseng & Tobacco Research Institute) ;
- Park, Kyung-Hwa (Plant Tissue Culture Research Unit, KRIBB) ;
- Kim, Yong-Hae (Korea Ginseng & Tobacco Research Institute) ;
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Yoon, Eui-Soo
(Department of Biology, Kongju National University) ;
- Kang, Tae-Jin (Neurbiotechnology Center, Ohio State University) ;
- Park, Kwang-Tae (Korea Ginseng & Tobacco Research Institute)
- Published : 1999.10.01
Abstract
Ginseng(Panax ginseng C.A. Meyer) is important medicinal plant but requires 4-year cultivation for root harvest because of slow growth. In contrast, ginseng callus and hairy roots grow vigorously and may Produce the same or more biologically active compounds for human health than natural ginseng roots. Therefore, ginseng callus and hairy roots can be used for commercial purposes. Polyacetylene, one of anti-cancer compounds in ginseng, was not detected in the callus cultured on the medium containing 2, 4-B, but cells derived from the callus growth was excellent, The ginseng calli cultured on the medium containing 2mg11 CPA and 0.05mg/1 BA was grown vigorously and produced panaxydol, one of ginseng polyacetylene. The biosynthesis of polyacetylene in callus was not affected by addition of NAA and sucrose in media. The SH medium was better than the MS medium for ginseng callus growth and biosynthesis of panaxydol. Another ginseng anti-cancer compounds, ginsenoside-Rg