Regulation of G-protein Coupled Inwardly Rectifying $K^+$ Channel Expressed in HEK 293 Cell by Phosphorylation

  • Kim, Jae-Hoon (Department of Physiology Gyeongsang National University College of Medicine) ;
  • Park, Choon-Ok (Department of Physiology Gyeongsang National University College of Medicin) ;
  • Kim, Yeon-Woong (Department of Biochemstry Gyeongsang National University College of Medicin) ;
  • Hong, Seong-Geun (Department of Physiology Gyeongsang National University College of Medicine)
  • Published : 1998.06.01

Abstract

Acetylcholine-activated $K^{+}$ ($K_{ACh}$) channels has been introduced as a typical G protein ( $G_{K}$)-coupled inwardly rectifying $K^{+}$ (GIRK) channel, which constructs with four subunit composed of two types of GIRK isoforms, GIRK1 and GIRK4 (or CIR) for the atrial $K_{ACh}$ channel.(omitted)d)d)d)

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