Effects of t-Butyl Hydrogen Peroxide on the Maxi-K Channels of Rat Brain

  • Shin, Jung-Hoon (Dept. of Physiology and Biophysics, lnha Univ. Coll. of Med.) ;
  • Suh, Chang-Kook (Dept. of Physiology and Biophysics, lnha Univ. Coll. of Med.)
  • Published : 1998.06.01

Abstract

Oxidation and reduction of amino acid residues in proteins affect their functional properties. Especially, redox modulation of ion channel activities has been reported in number of ion channel proteins. In this study, we investigated the effects of tertiary-butyl hydrogen peroxide (tBHP) on the large-conductance Ca$\^$2+/ -activated K$\^$+/(Maxi-K) channel of rat brain using lipid bilayer reconstitution technique.(omitted)

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