Enzymatic Properties of Low Affinity Vanadate-sensitive ATPase in the Microsomes of Tracheal Epithelial Cells

  • Jung Sakong (Dept. of Agricultural Chemistry, Chungbuk National Univ.) ;
  • Kim, Young-Kee (Dept. of Agricultural Chemistry, Chungbuk National Univ.)
  • 발행 : 1998.06.01

초록

Previously, we reported two types of vanadate-sensitive ATPases in the micro somes of tracheal epithelial cells, a high-affinity one and a low-affinity one. The low affinity vanadate-sensitive (LAVS) ATPase was sensitive to thapsigargin and cyclopiazonic acid, specific antagonists of ER-type Ca$\^$2+/-ATPase, and mediated microsomal $\^$45/Ca$\^$2+/ uptake, implying that the LAVS-ATPase is an ER/SR-type Ca$\^$2+/-ATPase.(omitted)

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