한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)

한국생물물리학회 (The Korean Biophysical Society)
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Zinc Finger-DNA Recognition: Transcriptional Repression via Zinc Finger Design and Selection

  • Kim, Jin-Soo (Basic Research Center, Samsung Biomedical Research Institute)
  • 발행 : 1998.06.01
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초록

Zinc fingers of Cys$_2$His$_2$ class constitute one of the most common DNA binding motifs in eukaryotes. Unlike other DNA binding motifs, zinc finger proteins recognize very diverse DNA sites, and their sequence specificities can be systematically changed by phage display.(omitted)

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