대한의용생체공학회:학술대회논문집 (Proceedings of the KOSOMBE Conference)

대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
권호 표지

심근허혈시 세포에서의 활동 전위 모델

A Model Study of Action Potential in Acute Myocardial Ischemia

  • 송진호 (연세대학교 보건과학대학 의용전자공학과) ;
  • 장성윤 (연세대학교 보건과학대학 의용전자공학과) ;
  • 정만길 (연세대학교 보건과학대학 의용전자공학과) ;
  • 이경중 (연세대학교 보건과학대학 의용전자공학과)
  • Song, J.H. (Department of Biomedical Engineering, College of Health Science, Yonsei University) ;
  • Jang, S.Y. (Department of Biomedical Engineering, College of Health Science, Yonsei University) ;
  • Jeong, M.K. (Department of Biomedical Engineering, College of Health Science, Yonsei University) ;
  • Lee, K.J. (Department of Biomedical Engineering, College of Health Science, Yonsei University)
  • 발행 : 1997.11.28
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초록

In this paper, we designed a myocaldial ischemia model based on L-R dynamic model including hyperkalemia and anoxia. Using the model, we simulated the effects of ionic concentration $[K^+]_o$ and intracellular $[ATP]_i$ on action potential in single cardiac cell. Also we evaluated this model by comparing the simulated results with that of other researches. In luther research, we are going to consider the effect of acidosis quantitatively.

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