Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Adenosine Inhibits ATP-induced Calcium Influx in PC12 Cells

  • Park, Tae-Ju (Department of Life Science and Basic Science Research Center, Pohang University of Science and Technology) ;
  • Park, Se-Young (Department of Life Science and Basic Science Research Center, Pohang University of Science and Technolog) ;
  • Song, Sook-Keun (Department of Life Science and Basic Science Research Center, Pohang University of Science and Technolog) ;
  • Kim, Kyong-Tai (Department of Life Science and Basic Science Research Center, Pohang University of Science and Technology)
  • Published : 1997.07.01
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Abstract

The regulatory role of A$\sub$2A/ adenosine receptors in P$_2$ purinoceptor-mediated calcium signaling was investigated in rat pheochromocytoma (PC12) cells. When PC12 cells were treated with 2-p-(2-carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine (CGS21680), a specific agonist of the A$\sub$2A/ adenosine receptor, extracellular ATP-evoked [(CA$\^$2+/)]$\sub$i/ rise was inhibited by 20%.(omitted)

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