한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)
- 한국생물물리학회 1997년도 학술발표회
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- Pages.31-31
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- 1997
Block of HERG Channels Expressed in Xenopus oocytes by External$Ca^{2+}$
- Kim, Injune (Dept. of Life Science, Pohang University of Science and Technology) ;
- Ho, Won-Kyung (Dept. of Physiology, Seoul National University, College of Medicin) ;
- Chung, Yu-Jeong (Dept. of Physiology, Seoul National University, College of Medicin) ;
- Earm, Yung-E (Dept. of Physiology, Seoul National University, College of Medicin) ;
- Lee, Chin-Ok (Dept. of Life Science, Pohang University of Science and Technology)
- 발행 : 1997.07.01
초록
Rapidly activating delayed K current (IKr) in cardiac muscles plays an important in repolarization. Expression of HERG cloned by the study on inherited LQT revealed that it encodes a potassium channel with biophysical properties similar to those of IKr in cardiac myocytes: outward currents activating on depolarization with large tail currents on repolarization, implying the inward rectifying property.(omitted)
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