Elevated SR $Ca^{2+}$ Channel Activity in Diabetic Skeletal Muscles

  • Kim, Won-Tae (Dept. of Agricultural Chem., Chungbuk Nat′l Univ.) ;
  • Kim, Hae-Won (Dept. of Pharmacol., Univ. of Ulsan Coll. of Medicin) ;
  • Kim, Young-Kee (Dept. of Agricultural Chem., Chungbuk Nat′l Univ.)
  • Published : 1997.07.01

Abstract

Dysfunctions of skeletal muscles have been frequently reported in chronic diabetic mellitus (DM). In order to investigate the molecular mechanisms of abnormal function, the junctional sarcoplasmic reticulum (HSR) vesicles of skeletal muscles were prepared from the control and the streptozotocin-induced diabetic rats.(omitted)

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