Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Characterization of Single Channel Properties of Cardiac $Ca^{2+}$ Release Channel in Rats Treated with the Immunosuppressant Drug, Cyclosporin A

  • Lee, Eun-Hui (Dept. of Life Science, Kwangju Institute of Science and Technology (K-JIST)) ;
  • Park, Chul-Seung (Dept. of Life Science, Kwangju Institute of Science and Technology (K-JIST) ;
  • Kim, Do-Han (Dept. of Life Science, Kwangju Institute of Science and Technology (K-JIST))
  • Published : 1997.07.01
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Abstract

Cyclosporin A (CsA) is widely used to suppress rejection in rcipients of solid organ or bone marrow transplants. A variety .of toxic side effects of this agent such as cardiotoxicity have been reported. However the underlying molecular mechanisms for the cardiotoxicity are not well resolved.(omitted)

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