Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Both Quantitative and Qualitative Alterations of $Ca^{2+}$ Release Channel in Heart are Induced by Chronic Treatment of an Immunosuppressant, Cyclosporin A

  • Kim, Do-Han (Department of Life Science, Kwangju Institute of Science and Technology (K-JIST))
  • Published : 1997.07.01
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Abstract

Chronic treatment with cyclosporin A (CsA) were shown to induce reversible alterations of contractile properties in rat heart. To define the molecular mechanisms underlying the physiological alterations, the $Ca^{2＋}$ release channel (CRC) and $Ca^{2＋}$-ATPase in rat sarcoplasmic reticulum (SR) were examined.(omitted)

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