Solution Conformation of an Antimicrobial Peptide Gaegurin 4

  • Suk, Jae-Eun (Biomol. Struct. Res. Unit, KRIBB) ;
  • Baek, Hwa-Jin (Institute for Molecular Biology and Genetics, Seoul National University) ;
  • Lee, Byeong-Jae (Institute for Molecular Biology and Genetics, Seoul National University) ;
  • Han, Kyou-Hoon (Biomol. Struct. Res. Unit, KRIBB)
  • Published : 1997.07.01

Abstract

Gaegurin 4 is an antimicrobial peptide found in the skin of a Korean frog, Rana rugosa, known for its "wound-healing" effect for years. This 37-residue basic peptide binds to cell membranes and forms ion channels like other antimicrobial peptides but does not exhibit hemolytic activity.(omitted)

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