Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)
- 1996.07a
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- Pages.35-35
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- 1996
NITRIC OXIDE (NO) DIRECTLY ACTIVATES CALCIUM-ACTIVATED POTASSIUM CHANNELS FROM RAT BRAIN RECONSTITUTED INTO PLANAR LIPID BILAYER
- Shin, Jung-Hoon (Dept. of Physiology and Biophysics, Inha Univ) ;
- Suh, Chang-Kook (Dept. of Physiology and Biophysics, Inha Uni) ;
- Sungkwon Chung (Dept. of Physiology, Chung-Ang Univ. College of Medicin) ;
- Uhm, Dae-Yong (Dept. of Physiology, Chung-Ang Univ. College of Medicine)
- Published : 1996.07.01
Abstract
Nitric oxide (NO) has been reported to have many roles in vivo ranging from the neurotransmitter in brain to the relaxant in smooth muscles. Recently, using inside-out patches, Bolotina et al. (1) showed that relaxing effect of NO is aortic smooth muscle is through direct activation of Ca2+-activated K+ channels (maxi-K), resulting in hyperpolarization. (omitted)
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