Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)
- 1996.07a
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- Pages.30-30
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- 1996
Cloning, Expression, and Characterization of Superoxide dismutase from Aquifex Pyophilus, a Hyperthermophilic Bacteria
- Rhim, Jae-Hwan (Structural Biology Center, KIST) ;
- Yesun Han (Structural Biology Center, KIS) ;
- Kim, Sung-Hou (Department of Chemistry and Lawrence Berkeley National Laboratory, University of Califoni) ;
- Yunje Cho (Structural Biology Center, KIST)
- Published : 1996.07.01
Abstract
A suproxide dismutase gene of Aquifex pyroprolus, a novel marine hypenhermophilic bacterium, was cloned, expressed, and characterized. The SOD of A pyrophilus (ApSOD) is an iron-containing homo-oligomeric protein with a monomeric molecular weight of 24.2 kDa. the amino acid sequence is similar to those of known Mn- and Fe-SODs from thermophilic archaea, and metal binding residues in all SOD sequences from different species are also conserved in A. pyrophilus SOD. (omitted)
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