대한예방의학회:학술대회논문집
- 대한예방의학회 1994년도 교수 연수회(역학)
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- Pages.169-179
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- 1994
B-mode ultrasound images of the carotid artery wall: correlation of ultrasound with histological measurements
- Gamble G. (Departments of Medicine, School of Medicine, University of Auckland) ;
- Beaumont B. (Departments of Anatomy, School of Medicine, University of Auckland) ;
- Smith H. (Departments of Medicine, School of Medicine, University of Auckland) ;
- Zorn J. (Departments of Medicine, School of Medicine, University of Auckland) ;
- Sanders G. (Departments of Medicine, School of Medicine, University of Auckland) ;
- Merrilees M. (Departments of Anatomy, School of Medicine, University of Auckland) ;
- MacMahon S. (Departments of Medicine, School of Medicine, University of Auckland) ;
- Sharpe N. (Departments of Medicine, School of Medicine, University of Auckland)
- 발행 : 1994.02.01
초록
B-mode ultrasound is being used to assess carotid atherosclerosis in epidemiological studies and clinical trials. Recently the interpretation of measurements made from ultrasound images has been questioned. This study examines the anatomical correlates of B-mode ultrasound of carotid arteries in vitro and in situ in cadavers. Twenty-seven segments of human carotid artery were collected at autopsy. pressure perfusion fixed in buffered 2.5% gluteraldehyde and 4% paraformaldehyde and imaged using an ATL UM-8 (10 MHz single crystal mechanical probe). Each artery was then frozen, sectioned and stained with van Gieson or elastin van Gieson. The thickness of the intima. media and adventitia were measured 'to an accuracy of 0.01 mm from histological sections using a calibrated eye graticule on a light microscope. Shrinkage artifact induced by histological preparation was determined to be 7.8%. Digitised ultra sound images of the artery wall were analysed off-line. The distance from the leading edge of the first interface (